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A Brief Review on the Principles of Human Cadaver Preservation and Monitoring of Microbial Degradation المعتصم عثمان أحمد

Putrefaction and decay of preserved cadaver and body parts is one of the major issues that the faculties of medicines in various third world countries are facing. In this study we focus on the meaning of body preservation, causes of putrefaction and we highlight our personal experiences at the Faculty of Medicine in Prince Sattam bin Abdulaziz University in KSA, in preserving the body cadavers. We studied different physical and chemical methods of preservation of cadavers and body parts at the faculty and their efficiency in preventing bacteria and fungi that cause putrefaction and decay.

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Bacterial Contamination of Saudi Arabian paper currency: A report from Al-Kharj المعتصم عثمان أحمد

Currency is a public support tool for exchange of commodity and services. It’s prevalent practice for acquiring bread to broast and bath to bed has connected all human being together irrespective of race and occupation. Currency notes along with their denomination values also carry pathogens if contaminated and will act as an agent for infection transference. Therefore the objective of this cross-sectional study was to assess the load microbial pathogens of paper currency collected in selected public places of Al-Kharj, Saudi Arabia.

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Pharmacognostical, Antibacterial and Antioxidant Studies of Aerial Parts of Pulicaria somalensis (Family: Asteraceae) المعتصم عثمان أحمد

Plant P. somalensis (family-Asteraceae), distributed all over the world, especially in North America, Europe, Southern Africa, South Western China, Central Asia and Mediterranean region except, of Antarctica continent . The family Asteraceae, which contains about 1,620 genera and 23,600 species, is one of the largest angiosperm plant families among the dicotyledonous . Few plants of this family are shrubs, creepers and climber but the majority of plants of this family is herbaceous in nature. There are several key elements present in this family, such as fused anthers, fruits with single ovules and capitulum inflorescence, which are used for the detection of their species . Many members of this rich family have long been used in folk medicines . Antibiotics were widespread in natural crude drugs and exercised since their innovation in the 20th century. However, the emergence of multi-drug resistant pathogens, it becomes a global challenge to the medical world to investigate an active antibiotic . It is now widely recognized that there is a need to develop novel antibiotic agents to minimize the risk of antimicrobial resistance. Most of the species of this genus have been well explored for their medicinal values. The standardization of P. somalensis can be achieved by stepwise pharmacognostic studies . Accurate identification and quality assertion of the preliminary materials are essential requirements to ensure the reproducible quality of herbal medicine, which will contribute to its safety and efficacy. The simple pharmacognostic method used in standardization of plant material includes its morphological and anatomical characters . Oxidative damage...

Evaluation of Antifungal Activity of Olive Oil Based Nanoemulsion المعتصم عثمان أحمد

Topical delivery as an option to oral delivery of drugs has several advantages such as reduced adverse effects, improved efficacy and patient compliance especially for the drugs that having extensive first effect metabolism . However, a very few number of drugs with low dose, low molecular weight and high octanol-water partition coefficients can be successfully delivered, because of the anatomical structure of the barrier layer of skin. Topical delivery is better than painful hypodermic injections that produce hazardous biological waste and causes disease transmission because of needle contaminations . To achieve successful transdermal drug delivery, enhancement of skin permeability is of prime concern. Recently several physical, electrical, chemical and biochemical techniques have been proposed to increase the permeability of the skin. Among these, modification of permeability by chemical method is most widely used owing to economical, simple and rapid. Chemical permeation enhancers either improve the solubility or partition coefficient or increase the diffusion of drugs across the skin. However these are always toxic and irritant to the skin. This led to quest of natural skin penetration enhancers. Oleic acid, an unsaturated fatty acid in olive oil has demonstrated skin penetration potential in various studies However, there is very limited permeation enhancement study of olive oil on human skin . Olive oil as such may be used as permeation enhance especially for lipophillic drugs. In one study on the use of olive oil in blood-vessel suturing, olive oil was found to be non-irritating when compared to Vaseline Paraffin oil ....

Pharmacognostical, Antioxidant and Antimicrobial studies of aerial part of Pulicaria crispa (Family: Asteraceae) المعتصم عثمان أحمد

The Plant P. crispa, family Asteracea, scattered all over the world. The family of Pulicaria species plant is generally divided into 12 sub-families and representing nearly 10% of all flowering plants . The approximately 1,620 genera and 23,600 species are known in this family. The majority of Asteracea plants are herbaceous in nature. Except, of the Antarctica continent, Astraceae family is distributed all over the world. P. crispa is used in traditional medicine for the treatment of various ailments . The plant has been used for many years in conventional medicine for the cure of heart diseases and as gastroprotective, due to its antioxidative nature . The oil of arial parts of P. undulata from Saudi Arabia was investigated by GC/MS and found it has rich in phenolic compounds and monoterpene hydrocarbons low in sesquiterpene .Some of Pulicaria species have been used as galactagogues, antiepileptics, antimicrobial, antifungal and antioxidant due to presence of active phytochemicals. This plant also used by the people of southern Egypt and Saudi Arabia to treat inflammation, insect repellent and as an herbal tea . A phytochemical study of the P. crispa (Forssk.) shows the presence of sesquiterpenes . The phytochemical investigation of the oils of some species showed the presence of monoterpenes, diterpenes and sesquiterpenes which showed antibacterial and antioxidant activities. The use of antibiotics has been exercised since their innovation in the 20th century anddue to the emergence of multi-drug resistant pathogens, it becomes a global challenge to the medical worldto explore anactiveantibiotica...

Calcium channel blocking activity of Mentha longifolia L. explains its medicinal use in diarrhea and gut spasm. n.rehman

Shah, AJ., Bhulani, NN., Khan, SH., Rehman, NU., Gilani, AH., 2010. Phytotherapy Research 24, 1392-7.

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Antispasmodic and vasodilator activities of Morinda citrifolia root extract are mediated through blockade of voltage dependent calcium channels. n.rehman

Gilani, AH., Mandukhail, SU., Iqbal, J., Yasinzai, M., Aziz, N., Khan, A., Rehman, NU., 2010. BMC Complementary and Alternative Medicine 10, 2.

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Pharmacological basis for the medicinal use of Holarrhena antidysenterica in gut motility disorders. n.rehman

Gilani, AH., Khan, A., Khan, AU., Bashir, S., Rehman, NU., Mandukhail, SU., 2010. Pharmaceutical Biology 48, 1240-6.

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Pharmacological studies on Hypericum perforatum fractions and constituents. n.rehman

Khan, AU., Gilani, AH., Rehman, NU., 2011. Pharmaceutical Biology 49, 46-56.

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Antidiarrheal and antispasmodic activities of Salvia officinalis are mediated through activation of K channels. n.rehman

Khan, A., Rehman, NU., AlKharfy, KM., Gilani, AH., 2011. Bangladesh Journal of Pharmacology 6, 111-116.

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